PUBLICATIONS IN SCI-JOURNALS

Kim D, Nguyen QTT, Lee S, Choi KM, Park JY, Lee EJ. Customized small-sized clinostat using 3D printing and novel polydimethylsiloxane culture dish. Microgravity, 2023 In press

Lee YJ, Lee EJ. Surgical site infection after cytoreductive surgery in patients with ovarian, fallopian tube, and primary peritoneal cancer, is an independent predictor of poor overall survival via significant delays in adjuvant chemotherapy. Eur J Gynecol Oncol 2023 In press

Ham S, Choi JH, Shin SG, Lee EJ. High visceral fat-to-muscle ratio is an independent factor that predicts worse overall survival in patients with primary epithelial ovarian, fallopian tube, and peritoneal cancer. J Ovarian Res 2023 Jan 21;16(1):19

Nguyen QTT, Rhee H, Kim M, Lee MY, Lee EJ. Lumbrokinase, a fibrinolytic enzyme, prevents intra-abdominal adhesion by inhibiting the migrative and adhesive activities of fibroblast via attenuation of the AP-1/ICAM-1 signaling pathway. Biomed Research International 2023 Jan 12; 2023:4050730

Lee EJ. Robotic-assisted removal of metastatic bulky pelvic lymph nodes followed by concurrent chemoradiation in a patient with FIGO stage IIIC2R cervical adenocarcinoma. Int J Gynecol Cancer 2022;32(3): SF005, http://dx.doi.org/10.1136/ijgc-2022-igcs.566

Shin SG, Lee EJ. Clinical Outcomes Associated with Surgical Site Infection in Epithelial Ovarian Fallopian, and Peritoneal Cancer Patients Undergoing Cytoreductive Surgery. J Surg Infect 2022;7(2):19-26

Lee EJ, Oh JA. Overcoming the limitations of single-site robotic myomectomy via the gradual turning out method without an accessory port, and a know-how Gyne Robot Surg 2022;3(2):27-32

Kim JH, Lee EJ. Single-Site Robotic Myomectomy without Accessory Instrument Compared with Two-Port Laparoscopic Myomectomy: A Propensity Score Matching Analysis. Gynecol Obstet Invest. 2022;87(1):70-8

Nguyen QTT, Park HS, Lee TJ, Choi KM, Park JY, Kim D, Kim JH, Park J, Lee EJ. DKK3, Downregulated in Invasive Epithelial Ovarian Cancer, Is Associated with Chemoresistance and Enhanced Paclitaxel Susceptibility via Inhibition of the β-Catenin-P-Glycoprotein Signaling Pathway. Cancers 2022 Feb 12;14(4): 924

Jang M, Park R, Park YI, Park Y, Lee JI, Namkoong S, Lee EJ, Park J. LNX1 contributes to cell cycle progression and cisplatin resistance. Cancers 2021 Aug 12;13(16):4066

Jung YJ, Kim HR, Kim MK, Lee EJ. A novel germline mutation in hMLH1 in three Korean women with endometrial cancer in a family of Lynch syndrome: case report and literature review. Hereditary Cancer in Clinical Practice 2021 Jun 3;19(1):28

Lee EJ, Cho M, Rho SB, Park J, Chae DA, Nguyen QTT. β-TrCP1-variant 4, a novel splice variant of β-TrCP1, is a negative regulator of β-TrCP1-variant 1 in β-catenin degradation. Biochem Biophys Res Commun. 2021 Feb;542:9-16

Cha YE, Park R, Jang M, Park YI, Yamamoto A, Oh WK, Lee EJ, Park J. 6-Azauridine Induces Autophagy-Mediated Cell Death via a p53- and AMPK-Dependent Pathway. Int J Mol Sci. 2021 Mar 14;22(6):2947.

Lee EJ, Nguyen QTT, Lee M. Dickkopf-3 in Human Malignant Tumours: A Clinical Viewpoint. Anticancer Res. 2020 Nov;40(11):5969-5979

Kim JH, Cha MJ, Kim MK, Chung YJ, Lee EJ. Disseminated primary pulmonary choriocarcinoma successfully treated by chemotherapy: a case report and literature review. Cancer Invest. 2020 Sep;38(8-9):493-501 

Lee EJ, Kang H, Kwon HJ, Chung YJ, Kim JH, Lee SH. Radiofrequency endometrial ablation with a novel endometrial tip for the management of heavy menstrual bleeding and abnormal uterine bleeding: A prospective study. Int J Hyperthermia. 2020; 37(1): 772-776.

Jeong S, Park SB, Lee EJ, Kim MK, Park H, Lee E. Intranodal Hemangioma in the Pelvic Cavity: A Case Report. Current Medical Imaging, 2020; 16:1182-1184

Shin IW, Park H, Kang H, Jung YJ, Lee EJ. Hybrid laparoendoscopic single-site surgery using a 2-mm mini-laparoscopic instrument versus conventional three-port laparoscopy for gynecologic adnexal diseases: a prospective randomized trial. Gynecol Obstet Invest. 2019;84(5):495-502

Jo D, Park R, Kim H, Jang M, Lee EJ, Jang IS, Park J. AMP-activated protein kinase regulates the expression of human telomerase reverse transcriptase. PLoS One. 2018 Nov 26;13(11): e0207864.

Jang M, Kim H, Park R, Jo D, Lee EJ, Oh WK, Park J. 2,2'-Methylenebis (6-tert-butyl 4-methylphenol) enhances the antitumor efficacy of belotecan, a derivative of camptothecin, by inducing autophagy. Oncotarget. 2017 Dec 1;8(70):115068-115078

Lee EJ, Kim DH. Vaginal morcellation using an electromechanical morcellator through the posterior cul-de-sac after laparoscopic myomectomy or subtotal hysterectomy: a retrospective, case-control study. Surgical Endoscopy, 2016 Nov;30(11):4865-4870

Seong SJ, Kim D, Lee KH, Kim TJ, Chung HH, Chang SJ, Lee EJ. Role of hormone therapy after primary surgery for endometrioma: A multicenter retrospective cohort study. Reproductive Science, 2016 Aug;23(8):1011-8.

Lee H, Lee EJ. HPV infection and p16 promoter methylation as predictors of ASC-US/LSIL progression. Cancer Cytopathol 2016 January 124(1), 58-65

Nguyen TM, Shin IW, Lee TJ, Park J, Kim JH, Park MS, Lee EJ. Loss of ITM2A, a novel tumor suppressor of ovarian cancer through G2/M cell cycle arrest, is a poor prognostic factor of epithelial ovarian cancer. Gynecol Oncol. 2015 Dec 12.

Lee EJ, Kim BR, Seo SH, Lee SH, Rho SB. Dickkopf-3 (DKK-3) obstructs VEGFR-2/Akt/mTOR signaling cascade by interacting of β2-microglobulin (β2M) in ovarian tumorigenesis. Cell Signal. 2015 Aug 14;27(11):2150-2159.

Park M, Han SS, Lee EJ, Byon M, Kim MY, Kim MK, Kim GJ. Primary cervical choriocarcinoma during viable intrauterine pregnancy. J Obstet Gynaecol Res. 2015 Aug;41(8):1291-4

Namkoong S, Lee KI, Lee JI, Park R, Lee EJ, Jang IS, Park J. The integral membrane protein ITM2A, a transcriptional target of PKA-CREB, regulates autophagic flux via interaction with the vacuolar ATPase. Autophagy. 2015 May 4;11(5):756-68.

Park JM, Kim MK, Chi KC, Kim JHm Lee SH, Lee EJ. Prognostic significance of aberrant loss of Dickkopf-3 in gastric cancer: Can it predict lymph node metastasis preoperatively? World J Surg. 2015 39:1018-1025

Lee MK, Jeong EM, Kim JH, Rho SB, Lee EJ. Aberrant methylation of VIM promoter in uterine cervical squamous cell carcinoma. ONCOLOGY 2014:86(5-6):359-69

Lee EJ, Park HM. Trends in lapaoroscopic surgery for hysterectomy in Korea between 2007 and 2009. J Obstet Gynecol Res 2014 June; 40(6): 1695-1699

Park MS, Dong SM, Kim BR, Seo SH, Kang S, Lee EJ, Lee SH, Rho SB. Thioridazine inhibits angiogenesis and tumor growth by targeting the VEGFR-2/PI3K/mTOR pathway in ovarian cancer xenografts. Oncotarget. 2014 (in press)

Park ST, Kim BR, Park SH, Lee JH, Lee EJ, Lee SH, Rho SB. Suppression of VEGF expression through interruption of the HIF‑1α and Akt signaling cascade modulates the anti‑angiogenic activity of DAPK in ovarian carcinoma cells. Oncol Rep. 2014 Feb;31(2):1021-9

Lim HK, Park JM, Chi KC, Lee EJ, Jeong EM. Disappearance of Serum Methylated p16 indicates Longer survival in patients with gastric cancer. J Gastric Cancer 2013:13(3):157-163

Ryu SW, Kim JH, Kim MK, Lee YJ, Park JS, Park HM, Kim DH, Lee SH, Lee EJ. Reduced expression of DKK3 is associated with adverse clinical outcomes of uterine cervical suamous cell carcinoma. Int J Gynecol Oncol 2013 Jan; 23(1):134-40

Kang WS, Cho SB, Park JS, Lee MY, Myung SC, Kim WY, Lee SH, Kim DH, Lee EJ. Clinico-epigenetic combination including quantitative methylation value of Dkk3 augments survival prediction of the patient with cervical cancer. J Cancer Res Clinic Oncol 2013 Jan;139(1):97-106

Lee EJ, Kim TJ, Choi CH, Lee JW, Lee JH, Bae DS, Kim BG. Uterine endometrial carcinoma: 10 years’ experience with long-term follow-up at a single Korean institution. Gynecol Obstet Inves 2012;74(4):313-9

Namkoong S, Lee EJ, Jang IS, Park J. Elevated level of human RPA interacting protein α (hRIPα) in cervical tumor cells is involved in cell proliferation through regulating RPA transport. FEBS Lett. 2012 Oct 19;586(20):3753-60

Ka H, Seo H, Choi Y, Shin J, Lee EJ. Analysis of Lysophosphatidic acid Receptors in the Uterine Endometrium During the Proliferative and Secretory Phases and in Endometrial Hyperplasic and Cancer Tissues in Human. Biology of Reproduction. 2012;87(1):404

Lee EJ, Kang H, Kim DH. A comparative study of laparoscopic radical hysterectomy with radical abdominal hysterectomy for early stage cervical cancer: A long-term follow-up. Eur J Obstet Gynecol Reprod Biol 2011 May;156(1):83-6.

Park K, Chung YJ, So H, Kim K, Park J, Oh M, Jo M, Choi K, Lee EJ, Choi YL, Song SY, Bae DS, Kim BG, Lee JH. AGR2, a mucinous ovarian cancer marker, promotes cell proliferation and migration. Exp Mol Med. 2011 Jan 4.

Lee EJ, McClelland M, Wang Y, Long F, Choi SH, Lee JH. Distinct DNA methylation profiles between adenocarcinoma and squamous cell carcinoma of human uterine cervix. Oncol Res. 2010;18(9):401-8

Lee EJ, Kim TJ, Kim DS, Choi CH, Lee JW, Lee JH, Bae DS, Kim BG. p53 alteration independently predicts poor outcomes in patients with endometrial cancer: A clinicopathologic study of 131 cases and literature review. Gynecol Oncol. 2010 Mar;116(3):533-8

Lee EJ, Park SM, Kim K, Kim BK, Lee TJ, Seo T, Jang IS, Lee SH, Kim S, Lee JH, Park J. Reduced expression of DRAM2/TMEM77 in tumor cells interferes with cell death. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1340-4.

Kim K, Lee EJ, Lee SH, Seo T, Jang IS, Park J, Lee JH. Species-specific variation of RPA-interacting protein (RIP) splice isoforms. BMB Rep. 2009 Jan 31;42(1):22-7.

Lee EJ, Jo M, Rho S, Park K, Yoo YN, Park J, Chae M, Zhang W, Lee JH. Dkk3, downregualted in cervical cancer, functions as a negative regulator of beta-catenin. Int J Cancer 2009 Jan 15;124(2):287-97.

Park J, Kim K, Lee EJ, Seo YJ, Lim SN, Park K, Rho SB, Lee SH, Lee JH. Elevated level of SUMOylated IRF-1 in tumor cells interferes with IRF-1-mediated apoptosis.Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17028-33.

Lee EJ, Jo M, Park J, Zhang W, Lee JH. Alternative splicing variants of IRF-1 lacking exons 7, 8 and 9 in cervical cancer. Biochem Biophys Res Commun. 2006 Sep 8;347(4):882-8

Lee SJ, Choi YL, Lee EJ, Kim BG, Bae DS, Ahn GH, Lee JH. Increased expression of calpain 6 in uterine sarcomas and carcinosarcomas: an immunohistochemical analysis. Int J Gynecol Cancer. 2007 Jan-Feb;17(1):248-53.  

Lee EJ, Deavers MT, Hughes JI, Lee JH, Kavanagh JJ. Metastasis to sigmoid colon mucosa and submucosa from serous borderline ovarian tumor: response to hormone therapy. Int J of Gynecol Cancer, 2006 Jan-Feb;16 Suppl 1:295-9.

Lee EJ, Mircean C, Shmulevich I, Wang H, Liu J, Niemistö A, Kavanagh JJ, Lee JH, Zhang W. Insulin-like growth factor binding protein 2 promotes ovarian cancer cell invasion. Molecular Cancer, 2005 Feb 2;4(1):7

Lee EJ, Kong G, Lee SH, Rho SB, Park CS, Kim BG, Bae DS, Kavanagh JJ, Lee JH. Profiling of differentially expressed genes in human uterine leiomyomas. Int J Gynecol Cancer, 2005 Jan-Feb;15(1):146-54

Tangjitgamol S, Erlichman J, Northrup H, Malpica A, Wang X, Lee EJ, Kavanagh JJ. Benign multicystic peritoneal mesothelioma: cases reports in the family with diverticulosis and literature review. Int J of Gynecol Cancer, 2005 Nov-Dec; 15(6):1101-7

AWARDS AND HONORS

Invited speaker, in The 7th World Congress on Breast Cancer, Cancer Research & Therapy, Las Vegas, NV, USA, Oct 20-22, 2022

Best Award for Fusion Research Project, Chung-Ang University, Nov 05, 2019

Invited speaker, in The 4th Symposium of Ease Asian Gene Therapy Innovative Group in Okayama, Japan, June 21, 2015

Invited speaker, in The 3rd Symposium of Ease Asian Gene Therapy Innovative Group in Suzhou, China, June 14, 2014

Invited speaker, in The 2nd Symposium of Ease Asian Gene Therapy Innovative Group/The 17th Meeting of the Japan Gene Therapy Interest Group, in Okayama, Japan, March 30, 2013

Best paper award from Korean Society of Assisted Reproduction on February, 2013

Best paper award from Korean Society of Assisted Reproduction on August, 2011

IS Award, The 62nd Annual Congress of the Japan Society of Obstetrics and Gynecology on April 23, 2010

Best paper award from Korean Society of Gynecologic Oncology and Colposcopy on May, 2003.

Best paper award from Korean Society of Gynecologic Oncology and Colposcopy on May, 2002.

2003 Avon-AACR International Scholar-in-Training Award

GRANTS

2020-2024: Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2020R 1A2C 1003536): The mechanism to chemo-resistance of high grade serous ovarian carcinoma.

2017-2020: Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2017R1D1A1B03033972): The mechanism to increase chemosensitivity by DKK3 in ovarian cancer.

2013-2016: Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2013R1A1A2009971): The regulation of WNT/beta-catein signaling by beta-TrCP1 splice isoforms in cancer cell.

2011-2013: The National R&D Program for Cancer Control, Ministry for Health and Welfare, Republic of Korea (1120280): The study of ITM2A gene in ovarian tumor

2010-2012: The Korea Science and Engineering Foundation (KOSEF) grant funded by the Korea government (MEST) (2010-0005333): The mechanism of Dkk3 to inhibit beta-catenin pathway.

2009-2012: Korea Health 21 R&D Project, Ministry of Health & Welfare, Republic of Korea (A085138): The development of DNA methylation markers for early detection of gynecologic cancers.